Information for Patients and Caregivers

Get ure-Na.

Hyponatremia Learning Resources for Patients and Caregivers

National Kidney Foundation


National Institute Of Health



  • 15g Urea per pouch
  • Easily mixes with water or juice
  • Clinically Studied & Guideline supported*
  • Safe, effective and cost sensitive
  • Proprietary flavor masking formula
  • May be Covered by health insurance via Prior Authorization. If not covered it may be a tax deduction qualified medical expense

Frequently Asked Questions

Q: Is ure-Na covered by health insurance?

A: ure-Na may be covered by health insurance. Your Health Care Provider will have to request coverage from your insurance through Prior Authorization. If ure-Na is not covered by insurance it may be a tax deduction qualified medical expense.

If your insurance approves coverage ure-Na can be ordered from most retail pharmacies. If your pharmacy is unable to order ure-Na, please call us at 1-844-980-9933. Let us know which pharmacy you use and we will reach out to them.

Ure-Na is on the VA National Formulary (VANF). It is listed as: UREA 15GM/PKT/PWDR,ORAL.

If insurance does not approve coverage, and ure-Na has to be paid for out of pocket it can be ordered at most retail pharmacies, but best price is usually found here at

Medical Foods like ure-Na, when recommended by a Health Care Provider are often a qualified tax deductible medical expense.

Medical Foods like ure-Na may also be purchased under a Health Saving Account (HSA). More information can be found by Clicking HERE to read the IRS guidance on this.

Q:How do I get ure-Na quickly?

A: ure-Na can be ordered from the pharamcy at most CVS and Rite-Aids. The Pharmacist will need the following NDC/Billing #:62350-0000-11 If you don't have CVS or Rite Aid in your area, ure-Na can be ordered from pharmacies that wholesale from Cardinal or McKesson. About 70% of all pharmacies wholesale from these two wholesalers. Walgreeens does not. You'll have to ask the pharmacy who they wholesale from. If they can't find ure-Na in their ordering system, having these two item numbers will help the pharmacy find it: McKesson item #: 3572344. Cardinal item #: 5286018.

Q: What is ure-Na?

A: ure-Na is flavor masked pharmaceutical grade urea with 15g of urea per single serve pouch. ure-Na is lemon-lime flavor. The pharmaceutical grade urea in ure-Na is not animal derived.

Q: What is hyponatremia?

A: Hyponatremia is a condition that occurs when the level of sodium in your blood is abnormally low relative to the amount of water in your blood. Sodium is an electrolyte. One role of sodium in the body is to help regulate the amount of water that is in and around your cells. In hyponatremia, one or more factors causes the sodium in your body to become diluted. When this happens, your body's water level rises and your cells begin to swell. This swelling can cause many health problems, from mild to life threatening.

Q: How does ure-Na or urea help my hyponatremia?

A: The urea in ure-Na helps remove excess water in your body without removing important electrolytes including sodium. This happens in the form of increased urine output without urinating out excess sodium.

Q: Is ure-Na safe for me to take?

A: Urea has been used for decades for the treatment of hyponatremia. Ure-Na is urea with a proprietary flavor and taste making formula making it palatable. Urea without the proprietary flavor and taste masking formula is very unpalatable and many people find the taste and flavor is too strong to ingest. The use of urea to treat hyponatremia is supported in multiple domestic and international guidelines that your Health Care Provider uses to guide the treatment of hyponatremia.

Q: Is ure-Na a prescription drug?

A: ure-Na is not a prescription drug. It is a Medical Food regulated differently than prescriptions drugs by the FDA. While ure-Na is not a prescription drug, it is to only be used while under the care of a health care provider.

Q: What is a Medical Food?

A: Unlike supplements, Medical Foods are regulated under the FDA Orphan Drug Act. They are for the management of specific diseases and are used and dosed under the supervision of a health care provider.