Information for Patients

Get ure-Na.

Hyponatremia Learning Resources for Patients and Caregivers

National Kidney Foundation


National Institute Of Health



  • 15g Urea per pouch
  • Easily mixes with water or juice
  • Clinically Studied & Guideline supported*
  • Safe, effective and cost sensitive
  • Proprietary flavor masking formula
  • May be Covered by health insurance on the medical side of benefit. If not covered it may be a tax deduction qualified medical expense
  • ure-Na is pronounced: you-ree-nah

If ure-Na is needed quickly.

If ure-Na is needed quickly, it can be ordered at most retail pharmacies for overnight delivery. To order ure-Na, the pharmacist will need the following NDC or National Drug Code number to find ure-Na in their ordering system: 62530-0000-11. Please call 1-844-980-9922 option #2 if you are having difficulty finding ure-Na in a local retail pharmacy.

Ure-Na is a Medical Food

Ure-Na is a Medical Food and is available to order without a prescription. However, ure-Na is only to be used and dosed under the care of a qualified health care professional. Hyponatremia is a complex disorder and a full clinical picture needs to be understood and analyzed so proper decision-making is used to find an appropriate therapeutic regimen.

Short video on how ure-Na treats hyponatremia


About Hyponatremia (low sodium)

Hyponatremia or low sodium, is a condition that occurs when the level of sodium in your blood is abnormally low relative to the amount of water in your blood.

Sodium is an electrolyte. One role of sodium in the body is to help regulate the amount of water that is in and around your cells.

In hyponatremia, one or more factors cause you to have too much water relative to sodium in your body. When this happens cells in your body begin to swell.

This swelling can cause many health problems from minor to moderate to life threatening.

Typical symptoms of hyponatremia are:

Confusion or brain fog
Balance issues
Problems walking
Abnormal tiredness

Consequences of severe hyponatremia may include:



Ure-Na is available in a box with 8 sachets containing 15g USP urea per sachet.

Calories in ure-Na

For some, especially people with diabetes the caloric content of ure-Na is important. Each sachet of ure-Na contains less than 15 calories. The calories are derived from the maltodextrin.

ure-Na ingredients

Ingredients in descending order: synthetically derived urea powder, natural flavors, maltodextrin, citric acid, calcium silicate, sucralose.

ure-Na and Celiac Disease

ure-Na contains maltodextrin. The maltodextrin used in ure-Na is corn derived not wheat derived.

Taking ure-Na with food.

ure-Na can be taken with or without food. A percentage of people taking ure-Na experience mild nausea when taking it. Taking it with food usually alleviates this.

Frequently Asked Questions

Q: Is ure-Na covered by health insurance?

A: Please see the Insurance section of this site, found at the top left of the home page for more in-depth information.

ure-Na may be covered by health insurance. Your Health Care Provider will have to request coverage from your insurance through Prior Authorization. If ure-Na is not covered by insurance it may be a tax deduction qualified medical expense.

ure-Na is on the VA National Formulary (VANF). It is listed as: UREA 15GM/PKT/PWDR,ORAL.

If insurance does not approve coverage, and ure-Na has to be paid for out of pocket it can be ordered at most retail pharmacies, but best price is usually found here at

Medical Foods like ure-Na, when recommended by a Health Care Provider are often a qualified tax deductible medical expense.

Medical Foods like ure-Na may also be purchased under a Health Saving Account (HSA). More information can be found by Clicking HERE to read the IRS guidance on this.

Q:How do I get ure-Na quickly?

A: ure-Na can be ordered from most retail pharmacies for overnight delivery. The pharmacist will need the following NDC number to locate ure-Na in their ordering system: 62530-0000-11. Please call us at 1-844-980-9922, option #2 if you are having difficulty ordering ure-Na at a local pharmacy.

Q: What is ure-Na?

A: ure-Na is flavor masked pharmaceutical grade urea with 15g of urea per single serve pouch. ure-Na is lemon-lime flavor. The pharmaceutical grade urea in ure-Na is not animal derived.

Q: How does ure-Na or urea help my hyponatremia?

A: The urea in ure-Na helps remove excess water in your body without removing important electrolytes including sodium. This happens in the form of increased urine output without urinating out excess sodium.

Q: Is ure-Na safe for me to take?

A: Urea has been used for decades for the treatment of hyponatremia. Ure-Na is urea with a proprietary flavor and taste making formula making it palatable. Urea without the proprietary flavor and taste masking formula is very unpalatable and many people find the taste and flavor is too strong to ingest. The use of urea to treat hyponatremia is supported in multiple domestic and international guidelines that your Health Care Provider uses to guide the treatment of hyponatremia.

Q: Is ure-Na a prescription drug?

A: ure-Na is not a prescription drug. It is a Medical Food regulated differently than prescriptions drugs by the FDA. While ure-Na is not a prescription drug, it is to only be used while under the care of a health care provider.

Q: What is a Medical Food?

A: Unlike supplements, Medical Foods are regulated under the FDA Orphan Drug Act. They are for the management of specific diseases and are used and dosed under the supervision of a health care provider.